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Welcome to our Lume community!

Prescribing Information

Send a Lucin prescription through any EHR to our partner pharmacy. Once received, the medication is dispensed and shipped directly to patients.

L-methylfolate calcium is standardized at 15 mg across all Lucin medications (clinically significant dose). The SSRI component is reduced ~10% from commercial reference dose to account for the complementary serotonergic effect of L-methylfolate. Ie. patient taking sertraline 25 mg, we recommend Sertralucin (Sertraline 22 mg and L-methylfolate calcium 15 mg).

Prescribing instructions

1. Pharmacy

Route prescriptions to Lume’s fulfillment
partner.
Who is Valiant pharmacy?
Valiant pharmacy is Lume's fullfillment partner. They batch manufacture + fullfill prescriptions
Valiant Pharmacy
NCPDP ID: 5755167
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2. Medication Details

Fill in the medication type, dose, and refill quantity.
Why is there a small decrease in SSRI dose?
SSRI dose is 10% decreased to balance the added serotenergic effects of l-methylfolate.
Why is there a small decrease in SSRI dose?
Consistent with our measured approach to medication, our formulation marginally decrease (10%) the SSRI dose to balance the added serotenergic effects of l-methylfolate.
Thank you! Your submission has been received!
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Why is there a small decrease in SSRI dose?
SSRI dose is 10% decreased to balance the added serotenergic effects of l-methylfolate.
Why is there a small decrease in SSRI dose?
Consistent with our measured approach to medication, our formulation marginally decrease (10%) the SSRI dose to balance the added serotenergic effects of l-methylfolate.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
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Why is there a small decrease in SSRI dose?
SSRI dose is 10% decreased to balance the added serotenergic effects of l-methylfolate.
Why is there a small decrease in SSRI dose?
Consistent with our measured approach to medication, our formulation marginally decrease (10%) the SSRI dose to balance the added serotenergic effects of l-methylfolate.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
Start Now
Why is there a small decrease in SSRI dose?
SSRI dose is 10% decreased to balance the added serotenergic effects of l-methylfolate.
Why is there a small decrease in SSRI dose?
Consistent with our measured approach to medication, our formulation marginally decrease (10%) the SSRI dose to balance the added serotenergic effects of l-methylfolate.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
Start Now

3. Notes

Add in the below details in the notes section of your EMR system. Be sure the patient’s email address is in the prescription.
L-methylfolate 15 mg
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What to expect

1

Send prescription

E-prescribe to our partner pharmacy and include your patient’s email address.

2

Payment coordinated

Your patient receives a secure email to confirm shipping and payment details.

3

Medication delivery

Medication ships in discreet packaging with expedited 2-day delivery after pharmacy fullfillment.

Frequently Asked
Questions

A combination medication is a single medication containing two or more active ingredients that have mechanistic complementarity. A common example you may be familiar with is Bactrim (Trimethoprim-sulfamethoxazole).

Escalucin, Fluoxlucin, Sertralucin, and Citalucin are combination antidepressant medications that are complexed with prescriptive L-methylfolate, which increases monoamine neurotransmitter synthesis while the SSRI blocks it's reuptake. Learn more here.

Prescription L-methylfolate enhances monoamine synthesis by supporting tetrahydrobiopterin (BH4)-dependent neurotransmitter production. Given its complementary mechanism to SSRIs, a modest reduction in the baseline antidepressant dose is utilized to mitigate potential serotonergic potentiation. For patients who are clinically stable and tolerating a given SSRI dose, a slight dose adjustment represents a conservative augmentation strategy while monitoring tolerability and therapeutic response.

Please ensure to include the patient’s email address so we can coordinate payment and shipping with them.

We will coordinate payment and shipping instructions with your patient at the email address included in the prescription. Medication prices can be found here.

We price our medication transparently, cutting out middlemen so that it can be as affordable as we can make it. To learn more about specific pricing, click here.

Check out our library page. If you have any follow up questions, feel free to reach out to us at hello@lumemh.com

Yes, SSRI+ can be prescribed from any EHR that connects to Surescripts. Direct prescriptions to our partner pharmacy, Valiant Pharmacy NCPDP ID: 5755167.

After you send the prescription to our partner pharmacy, we will email the patient with a secure payment link to collect payment for the medication + shipping address. Once this information is collected, our partner pharmacy will ship medication in discreet packaging via 2 day shipping.

We do our best to ensure that patients do not have lapses in their prescriptions as we understand this can be a major barrier that patients face in staying regimented taking their medication. For prescriptions that have a refill, we will automatically refill the prescription (24 hours prior to doing so, we will email the patient confirming the refill). For prescription that have no refills left, we will send you a reminder for a refill 10 days prior to when the refill would be needed.